A 31 - year - old woman showed up at an hand brake room experience shortness of breath , hives all over her body , and " abundant disgorgement " .

She had n’t been exposed to the Sun , wipe out anything strange , and did n’t have any insect bite upon inspection . Despite this , she was name with moderate anaphylaxis , which can be a severe , life - threatening allergic reaction , though doctors did n’t cognize now what make it .

The only   allergy   the unnamed woman   has is penicillin , which she was diagnosed with as a child . But , she had n’t taken any medication , let alone something she knew she was allergic to , doctors write in aBMJ Case Report .

However , she had late had oral sexuality with a man who was taking   amoxicillin - clavulanic acid treatment , which contains penicillin , leading the squad to conclude that the drug could have been transferred to the cleaning woman through " oral drug transfer " from her cooperator ’s semen .

The 32 - class - sure-enough man , also unnamed , had been take amoxicillin - clavulanic to deal an spike contagion for five twenty-four hours before the incident . His last dose was four hours before sex , which made its room into his semen , and was transferred to her during oral sex .

Anaphylaxis get in this way is highly rarified .

" An uncommon cause of anaphylaxis in womanhood isseminal plasma allergy , " the source fromtheHospital General Universitari d’Alacant inAlicante , Spain excuse in the case news report . " Coital sensitised reaction can … be cause in allergic women by the transfer of allergens ( drugs or food ) present at lowly concentrations in the seminal plasma of their mate . "

Seminal plasma allergyis rarefied , though it can touch up to 40,000 womanhood in the   US .

To the authors ' knowledge , this is the first cover case of a " suspicion of amoxicillin - induced anaphylaxis in a char after intimate contact with a piece who was study the drug , " and   the authors urged anyone with such an allergic reaction to be cognizant of the risk of transfer of training of allergens through semen .

" We opine that as clinicians , it is authoritative to be aware of this phenomenon so as to inform and foreclose potentially serious reactions in sensitized patients , " Susana Almenara , pencil lead author of the write up write . " We also commend prophylactic exercise during treatment with drugs that can induce hypersensitivity responses in partners . "

It took the womanhood a week to recuperate fully from the incident .