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from time to time , seemingly miraculous cases of humans lead in and out of hibernation - same state are reported . In 2006 , for example , a 35 - class - old humans was deliver on a snowy mountainside in Japan 24 days after go missing . He seemed to have survived by enter a state of nearly suspend invigoration : His organs had close down , hisbody temperature had droppedto 71 degree , and his metamorphosis had slowed almost to a standstill . later , the man made a full convalescence .
How could this extraordinary upshot have occurred ? Was the Japanese serviceman reallyhibernating like a bear ? And is the ability to move into and inflame from a protract slumber restricted to a few lucky individuals , or , in the right luck , can we all do it ?
In late years , many scientists have come to believe that outlandish natural selection stories are not mere flukes or medium exaggerations , but rather manifestation of a latent ability to hole up that all mankind possess .
Hydrogen sulfide : The dormancy gas
A cellular telephone life scientist nominate Mark Roth and his colleagues at the Fred Hutchinson Cancer Research Center in Seattle think that a gaseous compound called hydrogen sulfide may be the key to suspended animation .
In a watershed experiment in 2005 , the researcher induced hibernation for the first time in lab shiner by having them inhale large Department of State of hydrogen sulphide gas . The chemical substance bound with cell in berth of O , effectively shutting off allmetabolic processesin the mouse , and significantly tighten their physical structure temperature . Hours later , when scientists replaced the H sulphide with normal air , the mice come out of hibernation and showed no adverse effect from the ordeal .
" We recollect this may be a latent power that all mammals have potentially even humans and we ’re just harnessing it and turning it on and off , inducing a State Department of hibernationon demand , " Roth told LiveScience , a sister web site to Life ’s Little Mysteries , short after the publishing ofhis and his colleagues ' resultsin the journal Science .
Since then , researchers in the Roth Lab have continued experiment with the compound . They are study its essence onC. elegans , a species of nematode . " Worms have exactly the same answer as humans to H sulfide , " Jason Pitt , a postdoctoral fellow in the Roth Lab , recently differentiate Life ’s Little Mysteries . " If you get discover to H sulfide , you have what ’s called a ' knockdown . ' You forthwith suffer consciousness . If you persist there , you ’ll die . If you ’re removed and take into unfermented strain , you recover . These minor worms do the same matter . "
Because human beings and worms reply likewise to hydrogen sulfide photo , and becauseC. elegansis genetically round-eyed , do its reaction to the compound easy to decipher than ours , it is a perfect model organism for meditate the chemical ’s intriguing effects .
Someday , researchers trust the gas can be used to induce hibernation in humans , which could enable everything from long - distance space travelling to suspended animation during trauma recovery . necessitate to get to Jupiter , but ca n’t check enough food on your spaceship ? Just hibernate on the style . require a kidney transplant , but do n’t have an organ donor lined up ? Just go to log Z’s and wait for one .
But we ’re not at that point yet . " Because we do n’t know more about how hydrogen sulfide is working , we have n’t been able to do the same thing in people as we ’ve done in other organism , " Pitt state . " We ’re starting to larn more about how this agent does what it does . By canvass dissimilar related to molecules and how they work , we ’re starting to tease out what ’s going on . "
Even if gas exposure can finally be used to induce suspend animation in humankind , how does that explicate fluke causa of human race entering hibernation by themselves ?
" Since our science lab ’s initial oeuvre , a lot of multitude have shown that there is atomic number 1 sulfide endogenously in our bodies , " Pitt said . " There ’s growing evidence that it is this sort of inner regulative molecule that ’s present in all of us . But we do n’t yet understand what it ’s doing or how it works . "
Though they do n’t claim to know everything about it , the scientist do think the compound has been in us since life began , 3.5 billion age ago .
We ’re a lot like bacterium
" It make a lot of sense that world and other mammals would have a latent ability to enter suspended animation , " Pitt said . " Early in the story of the Earth we had no oxygen . However , you did have these sulfur chemical compound like atomic number 1 sulphide . "
" There are organisms out there today in extreme environments that respirate with hydrogen sulphide , " he continued . " presumptively we all come from those environments . Becausebiology hold its baggage around with it , it would not be surprising if humans had an ability to do some pretty ancient chemical reaction . We ’re talking about things that happen 3.5 billion years ago when oxygen first lead off to come along and when cyanobacteria go commute the Earth ’s interpersonal chemistry . "
Many types of bacterium are able to turn their metabolism on and off as a survival of the fittest chemical mechanism . consort to Pitt , we should n’t be much dissimilar .
" Our eucaryotic cellular telephone are symbiotic organism , he said . " Our mitochondria evolved from a bacterium . Basicallywe’re a lot more like bacteriathan we like to call back . "
